Lipids and Lipid Derivatives
Cayman Chemical C16 Sphingomyelin (d18:1/16:0), Purity: ≥98%, CAS: 6254-89-3, 1 mg
A naturally occurring sphingolipid; levels are elevated in the prefrontal cortex and cerebellum in a rat model of STZ-induced diabetes, as well as in the liver in mouse models of Niemann-Pick type C1 disease; plasma are decreased in patients with prostate cancer; has been used in model membranes with POPC and cholesterol in the study of lipid raft dynamics and membrane organization
Cayman Chemical Betulinic Acid, Purity: ≥97%, CAS: 472-15-1, 500 mg
An agonist of the bile acid receptor TGR5 (EC50 = 1 µM) and blocks fatty liver development in cells and mice given ethanol; reduces NF-κB signaling and expression of miR-33 in LPS-treated macrophages, increasing levels of ABCA1; inhibits replication of HIV-1 (IC50 = 1.4 µM) and has cytotoxic effects against cancer cells
Cayman Chemical C12 NBD Ceramide (d18:1/12:0), Purity: ≥98%, CAS: 202850-01-9, 1 mg
C12 NBD ceramide (d18:1/12:0) is a long-chain fluorescent ceramide analog that can be used for the measurement of alkaline and neutral ceramidase activity.{14063} It is hydrolyzed efficiently by alkaline ceramidase from P. aeruginosa and by neutral ceramidase from mouse liver. In addition, alkaline and neutral ceramidases from a variety of mammalian cell lines also hydrolyze C12 NBD ceramide (d18:1/12:0). Acid ceramidase does not appear to utilize C12 NBD ceramide (d18:1/12:0) as a substrate. The possibility exists forC12 NBD ceramide (d18:1/12:0) to also be applied to the measurement of ceramide kinase and/or sphingomyelin synthase activity.
Cayman Chemical Resolvin D2 Neurochemicals
A product of the action of 15- and 5-LO on DHA; dampens excessive neutrophil trafficking to sites of inflammation; reduces zymosan-stimulated PMN infiltration by 70% at 10 pg per mouse; reduces PAF-stimulated leukocyte adherence and emigration at 1 nM; stimulates nitric oxide production decreases leukocyte-endothelial interactions; reduces leukocyte and PMN infiltration, decreases production of pro-inflammatory cytokines, and promotes phagocyte-mediated bacterial clearance in a mouse model of sepsis
Cayman Chemical cis-2-Decenoic Acid, Purity: ≥95%, CAS: 15790-91-7, 25 mg
An unsaturated short chain fatty acid that is secreted by P. aeruginosa and induces a dispersion response in biofilms formed by gram-negative and gram-positive bacteria, as well as by the yeast C. albicans; promotes dispersion of P. aeruginosa biofilms over a concentration range of 1.0 to 10 nM
Cayman Chemical 1-hydroxy Vitamin D3, Purity: ≥95%, CAS: 41294-56-8, 10 mg
A synthetic prodrug which is converted to the vitamin D receptor agonist 1,25-dihydroxy vitamin D3 in vivo; suppresses the synthesis and secretion of parathyroid hormone in secondary hyperparathyroidism; supports bone growth; provides renal and cardiovascular protection during chronic kidney disease
Cayman Chemical Oleic Acid-13C5, Purity: ≥95%, CAS: 1255644-48-4, 10 mg
An internal standard for the quantification of oleic acid by GC- or LC-MS
Ambeed 4-(TERT-BUTOXY)-4-OXOBUTA-25G
4-(tert-Butoxy)-4-oxobutanoic acid, 25G, CAS# 15026-17-2, MFCD00273441, MOLWT: 174.19
Cayman Chemical Eicosapentaenoic Acid ethyl ester, Purity: ≥98%, CAS: 86227-47-6, 50 mg
A long-chain ω-3 fatty acid ethyl ester; dietary administration increases the ex vivo activity of hepatic β-oxidation enzymes at 41.4 g/100 g of total dietary fatty acids; reduces total hepatic triglyceride levels and increases the ω-3 fatty acid content of hepatic triglycerides and phospholipids, as well as increases the total levels of ω-3 fatty acids in rats; reverses increases in plasma cholesterol levels and reduces circulating triglyceride levels in rats fed a high-fat diet at 1 g/kg
Cayman Chemical Oleic Acidbiotin
An affinity probe designed to allow oleic acid to be detected in complexes with protein binding partners such as fatty acid binding proteins
Sigma Aldrich Fine Chemicals Biosciences 24R2425 Dihydroxyvitamin D
(24R)-24 25-Dihydroxyvitamin D3 is a metabolite of vitamin D3. It is known to increase bone volume and mechanical strength.(24R) 24 25-Dihydroxyvitamin D3-26 26 26 27 27 27-d6nbspis a deuterated metabolite of vitamin D3 wherein methyl protons of C-26 C-27 carbons are replaced by deuterium.
Sigma Aldrich Fine Chemicals Biosciences Eubacteria FISH probe Cy
Fluorescent In Situ Hybridization technique (FISH) is based on the hybridization of fluorescent labeled oligonucleotide probe to a specific complementary DNA or RNA sequence in whole and intact cells.1 Microbial FISH allows the visualization identification and isolation of bacteria due to recognition of ribosomal RNA also in unculturable samples.2 FISH technique can serve as a powerful tool in the microbiome research field by allowing the observation of native microbial populations in diverse microbiome environments such as samples from human origin (blood3 and tissue4) microbial ecology (solid biofilms5 and aquatic systems6) and plants7. Prokaryotic single cell life forms are divided into two domains called Bacteria and Archaea originally categorized as Eubacteria and Archaebacteria.8 However both terms Eubacteria and Bacteria are still being used in microbiology.Eubacteria probe recognizes most bacteria as it is complementary to a portionof 16S rRNA found in almost all bacteria